December 22, 2023
by PharmaReviews
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Chief Executive Office DRAP; Fake Degree case

Phamraceutical Review (Muhammad Usman) Our respected editor Muhammad Usman B. Pharmacy, LLB (Expert in Drug Law and pharmacy Jurisprudence, Advocate Lahore High Court, Lahore, Pakistan) has cover this case and reported to the staff of pharmaceutical review. He reported the major development in DRAP CEO Sheikh Akhter Hussain Fake Degree case as under,
Today (December 22, 2023), the FIA anti corruption circle has raided an office premises in F-10 Markaz on the pointataion of co- accused Raja Khurram Kiyani and Sheikh Akhtar Hussian ex-CEO DRAP During the raid, the FIA anti corruption circle has unearthed an international racket of fake degrees and diplomas being run by fake The Open International University Sri Lanka through its local agents Agents take USD 1000 for MD Degree and USD 1500 for PhD Degree, Agent namely Dr. Muhammad Amin Baig has been arrested, from the search of premises a large number of Blank Degree certificates, Emboss seal, Embose Stamps, stamps related to fake university, admission forms have been recovered. During the search, it has transpired that accused Dr. Amin Baig was also running a fake International Council for issuance of diplomas and certificates propounding it as an international council formulated by the Government of Pakistan, namely, the International Alternative Medical council. It is important to mention here that it’s the same racket of Open International University Sri Lanka that provided Sheikh Akhtar Hussain fake PhD degree. Both the Pakistani agents have been arrested. In due course of investigation, authorities in Sri Lanka will be approached through Interpol to investigate matter in Sri Lanka as well. Accused will be produce tomorrow in court for remand.

December 20, 2023
by PharmaReviews
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Former Chief Executive Officer (CEO) of the Drug Regulatory Authority of Pakistan (DRAP) Sheikh Akhtar Hussain has been booked in the fake PhD degree case, 

Phamraceutical Review (Muhammad Usman) Our editor Muhammad Usman B. Pharmacy, LLB Expert in Drug Law and pharmacy Jurisprudence (Advocate Lahore High Court, Lahore, Pakistan) has cover this case and reported to the staff of pharmaceutical review. The anti-corruption wing of the Federal Investigation Agency (FIA) lodged a case against former DRAP CEO Sheikh Akhtar Hussain for holding a fake PhD degree. The First Information Report (FIR) stated that Hussain possessed a dubious doctorate degree to get the CEO post of the country’s top drug regulator. The Sri Lankan Interpol confirmed the fake PhD degree as the degree-awarding institution was not recognised. Teams have been constituted to arrest the former DRAP CEO and raids were also conducted in different localities. Earlier, March,2019; The federal government has removed its top drug regulator for holding a dubious doctorate degree that he used to burnish his credentials when applied for the position of CEO Drug Regulatory Authority of Pakistan (DRAP). ‘Dr’ Sheikh Akhtar Hussain has also been drawing PhD allowance since 2002 on the basis of this degree recognised nowhere in the world. A report in a news paper  headlined “Not only his PhD, DRAP CEO’s appointment also faces questions” last month revealed how he rigged the system to clinch the top slot.

Ministry of National Health Services ordered inquiry into the matter after this report as it wrote to Higher Education Commission (HEC) for the verification of his degree. It replied that the degree-awarding institution, The Open International University, Colombo, is not recognised even in Sri Lanka, let alone in Pakistan. The ministry removed Sheikh Akhtar on Thursday, almost 10 days after receiving confirmation from the HEC. Intriguingly, Asim Rauf, a close aide of the sacked CEO, has been given the acting charge.

Sheikh Akhtar insisted when contacted in the past about the veracity of degree. Responding to The News’ queries, he had claimed that the university was recognised in Sri Lanka, he though didn’t dispute that it was not in the list of institutions approved by the HEC. A degree unapproved by the HEC can’t be used for job in Pakistan. Sheikh Akhtar Hussain claimed having done PhD in Pharmacology from The Open International University, Colombo (Sri Lanka). The HEC has negated claim that his degree awarding institution is recognised in Sri Lanka. “The Open International University, Colombo is not among the chartered universities/institutions of Sri Lanka,” the HEC wrote back to the ministry.

The university also doesn’t figure in the “International Handbook of Universities” published by Unesco, it has further been explained. “Therefore, as per policy, degrees awarded by non-chartered universities/institutions cannot be recognised by the Higher Education Commission/Government of Pakistan,” reads the HEC reply sent to the ministry.

Intriguingly, the ministry woke up to this disclosure only after media reports but didn’t bother to scrutinise his credentials at the time of selection done in December last year. Sheikh Akhtar was acting CEO by the time the selection process for the regular appointment was carried out. He was also ex-officio secretary of the policy board that was to constitute the scrutiny and interview committees. He is alleged to have manoeuvred the composition of these committees by inducting his choice officers to influence the decision making, a charge he denied in the past and said he didn’t participate in the meeting when the committees were formed.

However, the fact remains that his documents were not scrutinised during the selection process. Sheikh Akhtar replied to this objection in the past that the committee was supposed to determine the suitability of candidates for the post as per DRAP Act 2012, not to examine education credentials. But he didn’t mention that the process was carried out without framing the regulations in line with this Act which directs to make rules for the working of the above-mentioned committees. Even the Establishment Division’s directions were ignored which demanded the committee to satisfy itself regarding the genuineness of documents.

Sheikh Akhtar worked as acting CEO for almost 10 months before his induction as permanent CEO. He was first appointed by the PML-N government for three months in February but continued for another seven months courtesy a former senior judge.

In response to a question raised in the Senate, Health Minister Amir Kayani had revealed through written reply that during the hearing on April 25, 2018, (10 days before the expiry of Sheikh Akhtar’s tenure as acting CEO) “the senior judge verbally directed the then secretary Ministry of National Health Services, Regulations and Coordination, that Dr Sheikh Akhtar Hussain should continue as CEO DRAP till the appointment of regular CEO.”

Later, through another order in November 2018, the former judge directed the Health Ministry to prepare a summary “within a period of two days” for the appointment of permanent CEO which was eventually done in December. Call it a coincidence or well-thought out plan, Sheikh Akhtar, who continued as acting CEO on the verbal order of the judge, got appointed as the permanent CEO. However, an official source dismissed the impression of favouritism on part of the former judge.

December 20, 2023
by PharmaReviews
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FIA arrests fake degree maker in Islamabad

Phamraceutical Review (Editor – Muhammad Usman) Our editor Muhammad Usman B. Pharmacy, LLB (Expert Drug Law and pharmacy Jurisprudence Advocate Lahore High Court, Pakistan) has cover this case and reported to the staff of pharmaceutical review. The Federal Investigation Agency (FIA) Anti-Corruption Circle Islamabad has arrested a man involved in making fake degrees, reported 24NewsHD TV channel Wednesday.

The accused, identified as Khurram Shahzad Kayani, had posed as the Vice Chancellor of the fake Open International University of Sri Lanka and issued fake degrees to various people. The FIA recovered fake seals of the said university from his possession. The FIA said that the arrest was made under the direction of Deputy Director Anti-Corruption Circle Islamabad Afzal Khan Niazi, following the guidance of the previously arrested former CEO of Drug Regulatory Authority of Pakistan (Drap), Sheikh Akhtar Hussain.

Hussain had obtained his appointment as CEO in Drap on the basis of a fake degree issued by the same university. The FIA said that further investigation is underway and more revelations are expected during the interrogation of the accused.

December 20, 2023
by PharmaReviews
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Former chief of Pak drugs regulatory body arrested for holding fake PhD degree

Phamraceutical Review (Editor – Muhammad Usman); Our respected editor Muhammad Usman B. Pharmacy, LLB (Expert Drug Law and pharmacy Jurisprudence Advocate Lahore High Court, Pakistan) has cover this case and reported to the office and staff of pharmaceutical review. Ex CEO of Drug Regulatory Authority ‘Sheikh Akhtar’ Arrested in Fake Degree Case, Reportedly Withdrawn Rs. 2.5 Million/Month. The former CEO of the Drug Regulatory Authority of Pakistan (DRAP), Sheikh Akhtar Hussain, has been apprehended by the Federal Investigation Agency (FIA) on charges of possessing a fraudulent Ph.D. degree. This arrest follows a comprehensive investigation led by Afzal Niazi, deputy director of FIA Anti-Corruption Circle. Hussain allegedly resorted to extreme measures, faking his death twice, to elude charges related to the counterfeit degree.
The joint FIA team executed raids to capture Hussain, who stands accused of extensive corruption, amassing a staggering wealth exceeding Rs100 billion. His illicit activities include drawing salaries post-termination from government service and receiving allowances based on the forged Ph.D. Hussain’s arrest underscores a grave breach of trust and integrity within the regulatory body, raising concerns about the credibility of individuals occupying pivotal positions.
This case highlights the need for robust checks and balances in government institutions to prevent such instances of deception and corruption. The FIA’s decisive action serves as a deterrent against fraudulent practices within regulatory bodies, emphasizing the importance of transparency and accountability in upholding public trust.

December 20, 2023
by PharmaReviews
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Ex-DRAP chief Shaikh Akhtar Hussain arrested in corruption case

Phamraceutical Review (Editor- Muhammad Usman); Our respected editor Muhammad Usman B. Pharmacy, LLB (Expert Drug Law and pharmacy Jurisprudence Advocate Lahore High Court, Pakistan) has cover this case and reported to the office and staff of pharmaceutical review. Former Drug Regulatory Authority of Pakistan (DRAP) Chief Executive Officer (CEO) Shaikh Akhtar Hussain. was on Wednesday arrested when a special court rejected his bail in corruption, misuse of official position for personal gains and fake degree case.
Judge Shahrukh Arjmnad of Special Court Central (FIA Court) ordered arrest of ex-DRAP CEO, Shaikh Akhtar Hussain, in corruption and misuse of his official position as DRAP chief case here.

An FIR No.50/2023 was registered by Federal Investigation Agency (FIA) against Shaikh Akhtar Hussain on the allegations of fake degree, getting Rs 2.5 million LPR encashment allowance from tax payers money after termination on the order of Hon’ble Islamabad High Court by Federal government. Ex DRAP chief is also alleged in FIR for having assets of billions of rupees which are far beyond his known source of income. In at least two National Accountability Bureau (NAB) corruption references , Shaikh Akhtar Hussain, was reported as a “Dead man”.

Being a crooked of his own class, Shaikh Akthar Hussain managed to dodge NAB to avoid his arrest for years in the corruption cases. He, being a brain child of a powerful lobby of pharmaceutical tycoons functioning in Pakistan, managed to avoid his arrest in dozens of the cases of corruption for many years. The FIR registered against Shaikh Akhtar Hussain said that ex-DRAP chief used a fake degree of PHD to grab position as CEO DRAP in December 2018 and make huge financial gains illegally.

According to the FIR, the degree presented by Shaikh Akhtar Hussain to grab post of CEO DRAP was sent through Interpol for verification from Sri Lankan University which confirmed that the degree in question was fake.

Shaikh Akhtar Hussain had developed a gang of his likeminded officials in DRAP which oversaw fake degree to install him as DRAP chief and collude with him to make financial gains. Ineresstingly, the gang of officials which managed appointment of Akhtar Hussain as DRAP chief is still present in the authority. The same gang tampers DRAP record of DRAP to dodge FIA and other agencies to protest Akhtar Hussain from any punishment.

December 20, 2023
by PharmaReviews
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A mother’s letter to PM Imran Khan against ex-CJ Saqib Nisar that still remains unanswered

Phamraceutical Review (Editor – Muhammad Usman); Our respected editor Muhammad Usman B. Pharmacy, LLB (Expert Drug Law and pharmacy Jurisprudence Advocate Lahore High Court, Pakistan) has cover this case and reported to the office and staff of pharmaceutical review. 

Islamabad: Mother of Muhammad Usman, the owner of Everest Pharmaceuticals who was arrested from court room, is still waiting for response of Prime Minister Imran Khan on her 5-months-ago purported letter against former Chief Justice (CJ) Mian Saqib Nisar, wherein the former CJ is accused of adjudicating a case regarding drugs to favor his family members.

Usman was arrested from Supreme Court in March last year and his company was sealed by Federal Investigation Agency (FIA) after Drug Regulatory Authority of Pakistan (DRAP) had submitted report, during hearing of the case, accusing him of manufacturing and supplying spurious drugs.

However, the mother Samina Zaheer tells a different story. Leveling allegations on former CJ, she explains reasons ‘behind the curtain’ which culminated into arrest of her son. She claims that ex-CJ took notice of the drug related matters just for the sake of giving benefits to his family members, adding he heard the case which was directly in conflict of interest. According to her, she wrote a letter to Prime Minister Imran Khan in September last year in this regard. “I am writing you (Prime Minister) this application with last hope of Justice. My son (Muhammad Usman) was arrested on illegal verbal order of Honourable Chief Justice of Pakistan on 6th March 2018 and his factory was taken over illegally by Drug Regulatory Authority of Pakistan,” Samina’s purported letter stated. She says two daughters of ex-CJ Nisar are married with two sons of Mian Misbah-ur-Rehman. Mian Misbah was appointed as Federal Minister on 27th June, 2018 in interim government, she adds.

She says that Mian Misbah and his sons are the owners of three pharmaceuticals factories including Servier, PCW (Popular Chemical Works) and Schazoo.She questions whether ex-CJ Nisar could hear the cases regarding drugs, pharmaceuticals and DRAP when his family business was drugs manufacturing. “There is direct conflict of interest,” she claims. Usman’s mother questions how the suo motu could be taken on application of government official against a private person. 

According to her, five officials of Ministry of Health/DRAP were nominated by National Accountability Bureau (NAB) in a corruption case in 2001 wherein four accused persons were arrested but one Sheikh Akhtar Hussain saved himself from arrest by declaring himself dead. Another corruption reference of 2004 was filed by NAB. Hussain once again saved himself by declaring himself dead. She claims that Hussain, then acting CEO DRAP, filed an application to HR Cell of Supreme Court against Usman alleging that he was manufacturing spurious and unregistered medicines and his brother-in-law Raja Riffat Mukhtar, RPO Bahawalpur, registered a number of FIRs against Hussain and other DRAP officials. Usman’s mother questions how the suo motu could be taken on application of government official against a private person. Samina Zaheer in her letter raised another question that how orders to acting CEO DRAP could be given by the court regarding inspection of Everest Pharman when he is the complainant. 

It is pertinent to mention that the journalists covering Supreme Court on daily basis witnessed that ex-CJ Nisar did not allow Usman or his lawyer to speak during the course of hearing. Samina Zaheer in her letter raised another question that how orders to acting CEO DRAP could be given by the court regarding inspection of Everest Pharman when he is the complainant. She says that entire department of DRAP illegally entered Everest Pharma in the absence of even a single representative of Everest Pharma. Almost 150 officials of DRAP along with a huge number of unknown private persons remained in factory of Everest Pharma till midnight illegally and stole all documents, letterheads of Everest, medicines and Raw Materials etc. worth millions of rupees.

On the other hand, police and FIA separately investigated Raja Riffat Mukhtar, RPO Bahawalpur. Both agencies concluded that Mukhtar is one of the best officers of police with highest dignity and integrity and that neither he nor Usman filed any FIR against any official of DRAP, says the mother. She, however, leveled allegation that the then CJ called chairman NAB in his chamber instead of calling him in open court.

“My son never manufactured any spurious or unregistered medicines and he is still behind the bars since 6th March 2018. FIRs have been registered against him across Pakistan, although his factory is in Islamabad. Is it legal to register around 100 FIRs?” she says.“Then NAB, instead of explaining in open court that Sh Akhtar Hussain is a corrupt officer and his name is mentioned in two Corruption References of NAB and a new corruption inquiry has been started, tendered an apology regarding the issuance of show cause notice to Akhtar Hussain and withdrew the show cause notice,” the purported letter of Samina Zaheer stated.

“It is pertinent to mention here that Sh. Akhtar Hussain always gave extraordinary (legal or illegal) benefits to the Pharma companies of Mian Misbah-ur-Rehman (Samdhi of ex-CJ),” she stated. “My son never manufactured any spurious or unregistered medicines and he is still behind the bars since 6th March 2018. FIRs have been registered against him across Pakistan, although his factory is in Islamabad. Is it legal to register around 100 FIRs?” she says. “Can you (Prime Minister) compensate the agony and suffering of a mother due to illegal action of CJP,” her letter added.

She has further requested to initiate investigation against all corrupt officials of DRAP especially Sh. Akhter Hussain. According to the contents of letter, Hussain built an empire from his alleged corruption which include 4 Kanal Plaza (Zerena Mall) in Liberty Market, Lahore and a 4 Kanal House in Town Ship Lahore. Banami Business, according to letter, include 5 Pharma factories in Pakistan, 1 Pharma Factory each in India, China and Turkey, Biggest Pharma distribution in Lahore, Marz Pharmacy College Lahore and a GS1 Pakistan Company to provide software for printing of barcodes on medicines. However, when asked, she repeatedly avoided to produce any reference which could substantiate that Prime Minister Secretariat or Prime Minister House received the complaint/letter. However, the timeline and some factual background she narrates have some relevance to allegations. It is worthy to mention that the appropriate forum to file complaint against a judge is Supreme Judicial Council (SJC) and not Prime Minister. Chief Justice heads SJC as its Chairman. However legal experts believe that raising questions on veracity of allegation is hard keeping in view the contents of purported letter. Some from legal fraternity told this correspondent that if the matter, if investigated transparently, could constitute the charge of misuse of authority. Some of the lawyers, who had been critique of ex-CJ Nisar in his tenure, said that this is not the only case wherein such kinds of allegations are being leveled.

October 19, 2023
by PharmaReviews
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A symbolically dishonest and icon of corruption is appointed as principal of Lords College of Pharmacy, Lahore; The culprit got another opportunity to spoil the professional career of young learners and pharmaceutical academia after successfully damaging the college of pharmacy, University of Sargodha, Pakistan.

Pharmaceutical Review (Special Reporter). An icon of corruption and legend of dishonesties Dr. Sajid Bashir (Retired) has surprisingly got another chance to spoil the pharmacy profession. He is appointed as principal of a private teaching institution Lords College of Pharmacy, 53-M, Quaid-e-Azam Industrial Estate, Kot Lakhpat, Lahore, Pakistan in February 2021. That confirm the poor recruitment procedure, low teaching quality and business minded approach of the management of this institution. Because the corruption, dishonesties and irregularities of this idiot are internationally recognized and established. The detail is published and available online.

Principal of Lord College of Pharmacy, Lahore, Pakistan.

Additionally, this appointment mocks the quality assurance, official government policies and education standard in Pakistan. Because this stupid is symbolling all possible ways of corruptions in pharmacy academia. He has long and terrible history of corruption, and dishonesties as under,

  • An amazing character revealing the fundamental factors hurting the health standards, pharmaceutical patient’s care and teaching quality in developing countries.ادویات و صحت کے نظام کو مجروح کرنیوالی حقیقی اور مثالی شخصیت۔ http://dx.doi.org/10.52182/22205187.13022021 https://pharmareview.files.wordpress.com/2021/03/28-2021-feb-13-corruption-of-dean.pdf
  • The corruption of dean pharmacy, university of Sargodha needs attention and appropriate investigation. جامعہ سرگودہا کے شعبہ فارمیسی کے سرپرست کی بددیانتی وبد عنوانی۔ http://dx.doi.org/10.52182/22205187.7122018 | https://pharmareview.files.wordpress.com/2018/12/12-uos-corruption.pdf |
  • Pharmacy council of Pakistan, pharmacy discipline and pharmacist community. پاکستان فارمیسی کونسل کی ناکامی کا سدباب اور اسکے نظام صحت پر اثراب۔ http://dx.doi.org/10.52182/22205187.07112021 | https://pharmareview.files.wordpress.com/2021/11/2021-nov-7-pcp-role-2.pdf
  • An ideological compliance to establish the real state of Pakistan. فکری قومی تعبیر سے عملی ملکی تعمیر کا حقیقی سفر۔ http://dx.doi.org/10.52182/22205167.25062020 | https://pharmareview.files.wordpress.com/2020/07/dr.-taha-june-25-2020.pdf
  • Correction of pharmaceutical teaching institution is the start point of professional growth.ادویاتی   تعلیمی اداروں کی اصلاح، پیشہ فارمیس کی ترقی و خوشحالہ کا نقطہ آغاز۔ http://dx.doi.org/10.52182/22205187.13122016 | https://pharmareview.files.wordpress.com/2016/12/academic-and-admin-role.pdf
  • You will always be in our heart and memories تماری یادیں بسی ہیں دل میں افق کے اس پار جانے والو۔ http://dx.doi.org/10.52182/22205167.132022019 | http:/pharmareview.files.wordpress.com/2020/01/16-iqbal-and-dr.-rifat-3.pdf  
  • Lest we forget; Muhammad Iqbal (late) and dr. Riffat ul zaman (late)شہدافارمیسی کی عظمت کو سلام۔ http://dx.doi.org/10.52182/22205187.11022019 | https://pharmareview.files.wordpress.com/2019/02/13-iqbal-and-dr.-rifat-.pdf
  • M. Iqbal (late) – great leader, skilled pharmacist and outstanding person. عزت مآب محمد اقبال کی عظمت کو سلام ۔            http://dx.doi.org/10.52182/22205187.27082019 | https://pharmareview.files.wordpress.com/2019/08/13-iqbal-1-1.pdf
  • Pharmaceutical “fact sheet” 2014-15; released by prof. Dr. Taha nazir president pharmacist federation (Pakistan ) and pharmacist alliance, PPA. پیشہ فارمیسی کا حقائق نامہ 2014-2015 | http://dx.doi.org/10.52182/22205167.25012015 | https://pharmareview.files.wordpress.com/2015/01/21-fact-sheet-2014-15.pdf
  • The dilemma of pharmacy profession in Pakistan; a “white paper” regarding ppa election 2014پیشہ فارمیس کا المیہ ۔ قرطاس ابیٖض۔ | http://dx.doi.org/10.52182/22205187.21072014 | https://pharmareview.files.wordpress.com/2014/08/white-paper-election-corruption-2014.pdf
  • Lest we forget to our legend heroes تمہاری یادیں بسیں ہیں دل میں افق کے اس پار جانے والو۔ http://dx.doi.org/10.52182/22205187.19012020  |  https://pharmareview.files.wordpress.com/2021/03/15-iqbal-and-dr.-rifat.pdf
  • Prudential review of pharmacy teaching institutions in Pakistan. پیشہ فارمیسی کے ملکی تدریسی اداروں کا تجزیاتی جائزہ۔ http://dx.doi.org/10.52182/22205187.14062015 | https://pharmareview.files.wordpress.com/2015/06/academic-corruption-ff5.pdf
  • Review of evolving role and poor representation of pharmacy professional in Pakistan. ماہرین  ادویات کی ناقص نمائندگی اور پیشہ ورانہ بد حالی کی وجوہات و اسباب۔ | http://dx.doi.org/10.52182/22205187.25032016 | https://pharmareview.files.wordpress.com/2016/03/poor-rep-and-bad-prof-situa-of-pharm-prof-ff.pdf
  • Review of dissimilar roles, responsibilities and official duties of licensing (qualified person) and employee (working) pharmacists. قانونی اور ملازم فارماسسٹ کے پیشہ ورانہ کردار کا اصولی فرق۔ http://dx.doi.org/10.52182/22205187.13032017 | https://pharmareview.files.wordpress.com/2017/03/13-difference-among-the-licensing-and-employeed-pharmacist1.pdf
  • The poor and illegal representation of pharmacy profession in Pakistan.      پاکستان کا غیر معیاری ادویاتی نظام اور غیر اخلاقی پیشہ ورانہ نمائندگی ۔ http://dx.doi.org/10.52182/22205187.02022014 | https://pharmareview.wordpress.com/2014/02/02/poor-pharmaceutical-care-and-illegal-professional-representation-of-pharmacy-profession-in-pakistan/
  • Insufficient effort of the government of the punjab to improve the local health care.             حکومت پنجاب کے ادویاتی قوانین اور نظام صحت کے غیر یقینی اور ادہورے اقدامات۔ | http://dx.doi.org/10.52182/22205187.03082017 | https://pharmareview.files.wordpress.com/2017/03/8-insufficient-contribution.pdf
  • The potential reasons of poor representation and despicable professional situation in Pakistan.ماہرین ادویات کی ناقص نمائیدگی اور پیشہ ورانہ بد حالی کی وجوہات و اسباب۔ | http://dx.doi.org/10.52182/22205187.03082017    
  • An amazing symbol of corruption, and dishonesties revealed the fundamental factors of poor health standards, substandard pharmaceutical patient’s care and teaching quality in developing world, including Pakistan. | (pharmaceuticalsreview.com)
  • https://pharmaceuticalsreview.com/review-of-corruptions-of-prof-dr-sajid-bashir-chairman-and-dean-pharmacy-university-of-sargodha-2/

October 9, 2023
by Kiran Hayat
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According to a clinical experiment, a new medicine can provide people with epilepsy comfort.

Pharmaceutical Reviews (Associate Editor) The most frequent form of epileptic seizures, called focal seizures, take place when nerve cells in a specific area of the brain send out an abrupt, uncontrolled burst of electrical signals. This uncontrolled activity can cause strange behavior, moments of loss of awareness, and mood swings in addition to seizures. Although there are many treatments for controlling or reducing seizures, roughly one-third of patients still experience seizures, and some treatments may have serious adverse effects, according to specialists. According to a recent clinical trial led by experts at NYU Grossman School of Medicine, patients who added XEN1101 to their existing antiseizure medications had a 33% to 53% reduction in monthly seizures, depending on their dose. The eight-week treatment portion of the research saw an average 18% decrease in seizures in those who received a placebo. The majority of patients then agreed to continue the experiment, with the new medication helping around 18% of patients remain completely seizure-free after six months and about 11% of patients remain seizure-free after a year or longer.

October 8, 2023
by Kiran Hayat
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3D printing technique for treating brain damage.

Pharmaceutical Review (Associate Editor) By 3D printing human stem cells, researchers have created an artificial tissue that resembles a condensed cerebral cortex. The structures merged with the host tissue when inserted into mouse brain slices. The ground-breaking method created by University of Oxford researchers may one day offer specialized fixes for those who sustain brain damage. For the first time, the researchers showed that neuronal cells may be 3D printed to resemble the cerebral cortex’s structure. The findings were released in the journal Nature Communications today. The cerebral cortex, or outer layer of the brain, is frequently severely damaged in brain injuries, including those brought on by trauma, stroke, and surgery for brain tumors. This causes problems with cognition, movement, and communication. For instance, each Globally, traumatic brain injury (TBI) affects around 70 million people, with 5 million of these instances being severe or fatal. For severe brain injuries, there are currently no effective treatments, which has a significant impact on quality of life.Researchers at the University of Oxford used 3D printing to create a two-layered brain tissue. The cells convincingly integrated structurally and functionally into mouse brain slices after implantation.